Science 1 January 2010
The Rate and Molecular Spectrum of Spontaneous Mutations in Arabidopsis thaliana 
浣滆呭鍗曠苯浼犳硶浼犱簡30浠ｇ殑鎷熷崡鑺ol鐢熸佸瀷鐨5涓悗浠ｈ繘琛屽叏鍩哄洜缁勬祴搴忥紝涓庡師濮嬬殑鍩哄洜缁勫簭鍒楀姣斾竴鍏卞彂鐜99 涓⒈鍩虹殑鏇挎崲鍜 17鎴栧ぇ鎴栧皬鐨勬彃鍏ュ拰鍒犻櫎锛屾瘡涓浠ｅ熀鍥犵粍涓换浣曚竴涓⒈鍩哄彂鐢熺獊鍙樼殑鍙兘鎬т负7 脳 10E鈭9銆傚叾涓富瑕佺殑绐佸彉鏄疓:C鈫扐:T鐨勭獊鍙橈紝鍚屾椂涔熷彂鐜颁富瑕佺殑绐佸彉鏉ユ簮灏辨槸鐢插熀鍖栫殑C鑴辨皑鍩哄拰绱瀵艰嚧鐨勭獊鍙 銆
鐪嬩簡杩欑瘒鏂囩珷鎴戜滑杩樿兘璇村暐锛屽彧鑳借鍟ヨ棰橀兘鏈変汉鍋氾紝杩欑璇鹃涔熸湁浜哄仛杩樺彂浜唖cience锛屼笉杩囨剰涔夊掓槸寰堥噸瑕併
瀹屾暣Abstract瑙佷笅锛
Science 18 December 2009 Vol. 326. no. 5960
Virus of the Year:聽 The Novel H1N1 Influenza
鍏充簬浠婂勾绉戠爺杩涘睍鐨勪粙缁嶆ф枃绔狅紱鍏充簬H1N1鐨勬枃绔犮
Published Online December 3, 2009
Science DOI: 10.1126/science.1180278
Targeted 3′ Processing of Antisense Transcripts Triggers Arabidopsis FLC Chromatin Silencing
杩欑瘒鏂囩珷涓庝笂绡噉ature鏄悓涓疄楠屽鍋氱殑锛屽悓鏍烽兘鏄疐LC銆備綔鑰呴氳繃璇卞彉锛屽彂鐜颁簡涓や釜鎶戝埗RNA浠嬪鐨凢LC Chromatin Silencing铔嬬櫧锛孋stF64聽鍜 CstF77锛屼粬浠槸RNA 3′鏈鍔犲伐鍥犲瓙銆傚湪绐佸彉浣撲腑锛孎LC鐨勬涔夎浆褰曟湰涓嶅彈褰卞搷锛屼絾鏄湪FLC鐨勫弽涔夎浆褰曟湰淇グ涓紝CstF64鍜孋stF77鏄繀椤诲緱锛屼竴涓壒寮傜殑RNA缁撳悎铔嬬櫧寮曞浜嗕粬浠笌閭昏繎鐨勫弽涔塸olyA鐨勬椿鎬э紝杩欑鐗瑰紓鐨勪慨楗板姞宸ュ紩璧风粍铔嬬櫧鍘荤敳鍩哄寲閰剁殑娲绘т粠鑰屾姂鍒禙LC鐨勬鍚戣浆褰曘傚弽涔夎浆褰曟湰3′鏈鐨勪慨楗版潵璋冭妭姝ｄ箟杞綍鏈殑娲绘э紝涔熻涔熸槸涓涓櫘閬嶆満鍒躲傝繖涓ょ瘒鏂囩珷鐪熸紓浜紒鍋氬熀纭绉戠爺灏卞簲璇ヨ繖鏍凤紝鍙戠幇鏂扮殑鏈哄埗锛屽畬鍠勬棫鐨勮蹇碉紝姒滄牱鍟婏紒
Science 4 December 2009
Structural Mechanism of Abscisic Acid Binding and Signaling by Dimeric PYR1
鍙堜竴绡嘇BA鍙椾綋缁撴瀯鐨勬枃绔狅紝Science鐨刟rticle鍟婏紝鏈杩戝緢鐏晩銆
鎺ㄨ崘杩欎釜缃戝潃锛http://www.hjcz.org/bbs/read.php?tid=219399&page=e&fpage=1 (鍏充簬09骞碅BA鐨勯噸瑕佹枃鐚)
Science October 29, 2009
A Simple Cipher Governs DNA Recognition by TAL Effectors
Breaking the Code of DNA-Binding Specificity of TAL-Type III Effectors
鎴戜滑鐭ラ亾锛岀梾鍘熻弻浼氶氳繃涓夊瀷鍒嗘硨绯荤粺灏唀ffector铔嬬櫧娉ㄥ叆妞嶇墿缁嗚優鍐呰揪鍒拌嚧鐥呯洰鐨勶紝Xanthomonas锛堥粍鍗曡優鏉嗚弻锛夋湁涓绉峞ffector铔嬬櫧鏄疶AL (transcription activator-like) effectors锛屼粬鍙互閫氳繃缁撳悎骞舵縺娲绘鐗╀綋鍐呯殑鍩哄洜杈惧埌鑷寸梾鐩殑銆傝繖绉嶈泲鐧芥湁34涓皑鍩洪吀搴忓垪姣旇緝閲嶈锛屽叾涓12浣嶅拰13浣嶇殑娈嬪熀鏈夌潃澶氭佹э紝鎴戜滑鎶婅繖绉嶅鎬佹хО浣渞epeat variable-diresidue (RVD)锛岄氳繃鐮旂┒鍙戠幇RVD鍐冲畾浜嗗畠鎵缁撳悎鐨凞NA搴忓垪锛屼竴绉峈VD瀵瑰簲涓绉嶆牳鑻烽吀搴忓垪锛屽苟涓斿叿鏈夊吋骞舵э紝HD = C, NG = T, NI = A, NS = A,C, G, or T, NN = A or G, IG = T.杩欐牱鎴戜滑灏卞彲浠ラ娴嬪嚭涓浜沞ffector铔嬬櫧鎵璋冩帶鐨勯澏鍩哄洜锛屽苟涓旇繖椤瑰彂鐜板浠ュ悗鐮旂┒鍜岀敓鐗╂妧鏈殑寮鍙戝叿鏈夐噸瑕佷綔鐢紒
Science鏈鏂扮殑涓鏈燂紝鍏充簬Spatial Cell Biology鐨勫嚑绡囨枃绔狅細
浠嬬粛锛 Location, Location, Location
娴呰堪锛 Anatomic Demarcation of Cells: Genes to Patterns
璇勮锛
Actin, a Central Player in Cell Shape and Movement
Subcellular mRNA Localization in Animal Cells and Why It Matters
The Extracellular Matrix: Not Just Pretty Fibrils
Cell Signaling in Space and Time: Where Proteins Come Together and When They鈥檙e Apart
涓婂懆鍚姤鍛婂惉浜鸿杩欏懆鐜夌背鍩哄洜缁勭殑鏂囩珷瑕佸嚭鏉ワ紝鏋滅劧锛宻cience涓婁竴杩炵櫥浜3绡囩帀绫崇浉鍏崇殑鏂囩珷锛岄兘鏄編鍥藉仛鐨勶紝鎹缇庡浗浣悶姘寸ɑ锛氱帀绫冲ぇ姒傛槸5锛95锛屼腑鍥芥濂界浉鍙嶏紝鎰熷叴瓒ｇ殑鑷繁鐪嬬湅鍚с
The B73 Maize Genome: Complexity, Diversity, and Dynamics
Paternal Dominance of Trans-eQTL Influences Gene Expression Patterns in Maize Hybrids
A First-Generation Haplotype Map of Maize
闄勪笂鍚屾湡鐨勮瘎璁:聽聽 Solving the Maze
Science 6 November 2009
A Type I鈥揝ecreted, Sulfated Peptide Triggers XA21-Mediated Innate Immunity聽聽 [涓嬭浇]
Xa21澶у閮戒笉闄岀敓锛屾嵁璇存槸姘寸ɑ涓涓涓浘浣嶅厠闅嗗嚭鏉ョ殑鍩哄洜锛1995骞寸敱瀹嬫枃杩滃崥澹厠闅嗗彂鐜帮紝浣滆呭埄鐢ㄩ珮鏁堟恫鐩歌壊璋卞湪Xanthomonas oryzae pv. oryzae涓婃竻涓壘鍒颁簡涓涓194aa鐨勬皑鍩洪吀锛孨绔17涓猘a锛坅xYS22锛夊氨瓒充互婵娲籜a21锛屼絾鏄己灏憈yrosine sulfation灏嗗け娲汇備綔鑰呭張璇佹槑浜哫a21瀵筧xYS22鐨刡inding鍜岃瘑鍒槸蹇呰鐨勶紝鑰屼笖axYS22鍦ㄦ墍鏈塜anthomonas oryzae pv. oryzae鐨勭敓鐞嗗皬绉嶄腑閮芥槸淇濆畧鐨勶紝璇佹槑浜咥x21鏄竴涓狿AMP锛坧athogen-associated molecular pattern锛夛紝Xa21鏄瘑鍒玃AMPs鐨勭梾绋嬭瘑鍒泲鐧斤紙pattern recognition receptor锛夈
鍚岃绡囷細http://et83214.s126.288idc.com/?p=129
Sci. Signal, 6 October 2009
Coordinated Responses to Oxygen and Sugar Deficiency Allow Rice Seedlings to Tolerate Flooding
杩欐槸鍙戝湪銆婄瀛︹斾俊鍙蜂紶瀵笺(Science Signaling)涓婄殑鏂囩珷锛岃鏈熷垔闅跺睘浜庡浗闄呴《灏栨湡鍒娿婄瀛︺(Science)闆嗗洟锛屼笅闈㈤檮涓婄瀛︾綉鐨勬姤閬擄紝涔熺渷寰楁垜缈昏瘧浜嗐
鐮旂┒鍥㈤槦鎸囧嚭锛屾饭姘存槸涓涓叏鐞冩х殑閲嶅ぇ鐏惧锛岄氬父瀵艰嚧浣滅墿缂烘哀鑰屽仠姝㈢敓闀跨敋鑷虫浜★紝鍥犳閫犳垚涓ラ噸鐨勫啘涓氭崯澶便傛按绋绘槸鍞竴鑰愭饭姘寸殑涓昏浣滅墿锛屼絾鏄垎瀛愭満鍒朵竴鐩存湭琚牬瑙ｃ
鏈瘒璁烘枃閲嶈鐨勮础鐚槸娓呮鍛堢幇鈥滆泲鐧芥縺閰垛(CIPK15)涓鸿皟鎺ф按绋昏愭饭姘寸殑鍏抽敭鍩哄洜銆傜爺绌跺洟闃熷彂鐜帮紝褰撴按绋荤瀛愬湪娣规按鐘舵佷笅锛屽皢缂烘哀璁伅浼犻掑埌CIPK15锛屾帴鐫鍐嶈皟鎺х粏鑳炲唴鍏锋湁鐩戞祴鑳介噺澶氬鍙婃劅搴旈嗗鐨勫鍔熻兘铔嬬櫧婵閰(SnRK1A)锛岀劧鍚庨忚繃绯栬鎭紶閫掗斿緞鍦ㄦ按绋荤瀛愬唴澶ч噺鍒堕犳穩绮夋按瑙ｉ叾(amylase)灏嗘穩绮夎浆鍖栨垚绯栵紝鍚屾椂澶ч噺鍒堕犻厭绮捐劚姘㈤叾(alcohol dehydrogenase)灏嗙硸鍙戦叺浜х敓鑳介噺(ATP)锛屼娇绉嶅瓙鏈夎冻澶熺⒊姘村寲鍚堢墿鍙婅兘閲忚岃兘澶熷湪姘翠腑鍙戣娊銆傜瓑灏忚嫍蹇熺敓闀胯嚦姘撮潰鍙互鍛煎惛鏇村绌烘皵鍚庯紝鏍归儴浠ュ悓鏍峰師鐞嗗埗閫犵⒊姘村寲鍚堢墿鍙婅兘閲忥紝鑰屼娇妞嶆牚鍙湪鍗婃饭姘寸ɑ鐢颁腑鐢熼暱銆傚叾浠栬胺绫讳綔鐗╁強鏉傝崏骞舵棤杩欎簺鑳藉姏锛屽洜姝ゆ棤娉曞湪姘翠腑鍙戣娊鍙婄敓闀裤
浣欐窇缇庣爺绌跺憳鎸囧嚭锛屾按绋讳笉鎬庝箞鍠滄娣规按锛屼絾鏄彲浠ュ繊鑰愭饭姘淬傚洜姝わ紝浼犵粺绋诲啘鐨勬櫤鎱ф槸鍒╃敤娣规按鏂瑰紡鍘婚櫎鏉傝崏锛屽彲浠ュぇ閲忓噺灏戜汉宸ュ強闄よ崏鍓傘傚洜鑰岀洰鍓嶅叏鐞80%鐨勬按绋荤敯锛岃棄姝よ曠鏂瑰紡鏉ョ敓浜ц冻浠ュ吇娲诲叏鐞冭繎鍗婃暟浜哄彛鐨勭ɑ绫炽
姝ょ瘒璁烘枃鍙戠幇CIPK15瀵规按绋昏曚綔涔冭嚦浜虹被鐢熸椿鐨勯珮搴﹁础鐚紝鐢辨鍙銆傜敱浜庡彴椋庣瓑澶╃劧鐏惧锛屽父閫犳垚鍐滀綔鐗╂饭姘翠箣閲嶅ぇ鎹熷锛屾湰鐮旂┒涔熷彲浠ュ崗鍔╄偛鍑哄悇绉嶈愭饭姘翠綔鐗╋紝鍑忓皯姘存崯銆
Science. 2009 Aug 21;325(5943):998-1001
Loss of function of a proline-containing protein confers durable disease resistance in rice.聽聽聽 [涓嬭浇]
鍙︽湁璇勮鐩稿叧锛Plant genetics. New strategy promises lasting resistance to a rice plague.
绾㈠啗闀垮緛杩欎釜甯栧瓙鏈変笅杞斤細http://www.hjcz.cn/bbs/read.php?tid=206622
Science鏂囩珷灏变笉瑕佸璇翠簡銆備互鍓嶇殑绋荤槦鐥呭熀鍥犻兘灞炰簬NBS-LRR锛岃繖涓熀鍥犳槸渚嬪銆
Science (2002);297聽聽 DOI: 10.1126/science.1074973
Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi聽聽 [涓嬭浇]
杩欐槸浠婂勾鏈卞仴搴风粰鐮斾竴瀛︾敓涓婅鏃剁粰鐨勮璁鸿鏂囩珷锛岃櫧鐒舵湁浜涜佷簡锛02骞寸殑锛屼絾鍐呭杩樹笉閿欙紝瀵逛簬浜嗚В灏廟NA鍜岀敳鍩哄寲鏄瘒绠鍗曟槗璇荤殑鏂囩珷銆
鐪熸牳鐢熺墿鐨勫紓鏌撹壊璐ㄥ尯鍩熷瓨鍦ㄩ珮瀵嗗害鐨勯噸澶嶅簭鍒楀拰杞骇瀛愶紝鍚屾牱涔熷瓨鍦ㄤ慨楗扮殑缁勮泲鐧斤紝骞朵笖褰卞搷浜嗗熀鍥犵殑琛ㄨ揪鍜屾煋鑹蹭綋鍒嗙銆傚湪瑁傛畺閰垫瘝涓紝浣滆呮暡闄や簡argonaute, dicer, and RNA-dependent RNA polymerase绛変笌RNAi鏈夊叧鐨勫熀鍥狅紝缁撴灉鍙戠幇瀵艰嚧浜嗘贩涔辩殑鏉ヨ嚜寮傛煋鑹茶川鍖哄煙杞綍鏈殑鑱氶泦銆傚悓鏃朵即闅忕潃鏁村悎鍒板紓鏌撹壊璐ㄥ尯鍩熻浆鍩哄洜杞綍鐨勫幓鎶戝埗锛岀粍铔嬬櫧 H3 lysine-9 鐢插熀鍖栫殑缂哄け锛屼互鍙婄潃涓濈矑鍔熻兘鐨勬崯浼ゃ傛垜浠涓猴紝鐫涓濈矑閲嶅搴忓垪浜х敓鐨勫皬RNA閫氳繃RNAi鐨勬満鍒朵綔鐢ㄤ簬骞朵繚鎸佸紓鏌撹壊璐ㄧ殑褰㈡垚銆
Science Signaling锛2009 Oct 6;2(91):ra61.
Coordinated responses to oxygen and sugar deficiency allow rice seedlings to tolerate flooding.
鍙版咕绉戝瀹跺彂鐜扮殑铔嬬櫧婵閰禖IPK15(calcineurin B鈥搇ike (CBL)鈥搃nteracting protein kinase)锛屽彲浠ヨ皟鑺傛劅搴斿洜瀛怱nRK1A锛屾縺娲绘按绋昏愮己姘х殑涓绯诲垪閫傚簲閫斿緞銆侰IPK15鍦ㄦ按绋绘姉姘存饭涓捣閲嶈浣滅敤銆
璇勮 Comments